GSE244515

GSE244515 is the GEO accession Li et al. 2025 used for 11 healthy-control PBMC single-cell RNA-seq samples.

Use in Li et al. 2025

  • Li et al. 2025 combined 11 healthy-control individuals from GSE244515 with 37 T2D patients from GSE268210.
  • Li et al. 2025 used Harmony integration to reduce batch effects across the combined single-cell data.
  • Li et al. 2025 used the healthy-control samples as group D in the T-cell metabolic subtype analysis.

Relevance

  • This accession is important because Li et al. 2025’s healthy-control comparison does not come from the same accession as the T2D cases.
  • The cross-accession design makes batch correction and cohort comparability central to interpretation.
  • For this paper workspace, GSE244515 should be tracked as a control-data source, not as a T2D dataset.

Sources