Home page
This site is the public entry point for a manuscript workspace on type 2 diabetes, peripheral blood mononuclear cells, and ancestry-aware immune profiling. It connects the draft manuscript, project rationale, and source-backed evidence notes used to support the paper.
Start Here
- Project hub — research question, paper goals, core pages, and open questions.
- Manuscript draft — section-level draft pages for the paper.
- Paper evidence map — synthesis table connecting claims, sources, confidence, and manuscript use.
Manuscript Draft
Evidence And Context
- PBMC immune changes in type 2 diabetes
- Single-cell PBMC profiling in type 2 diabetes
- Ancestry-associated immune differences
- Ancestry-specific T2D genetic mechanisms
- Ancestry x PBMC immune changes in T2D
- Ancestry-specific T2D genetic mechanisms x PBMC immune changes
Key Literature Notes
- Gu et al. 2024: Single-cell PBMCs in T2D
- Tkachenko et al. 2024: T2D transcriptomic landscape
- Tkachenko et al. 2025: Cross-study blood transcriptomes in T2D
- Li et al. 2025: Immunometabolic alterations in T2D
- Markelova et al. 2025: Genetic heterogeneity of T2D across Russian ancestry groups
How To Read This Site
The manuscript/ pages contain draft paper prose. The concepts/, references/, and synthesis/ pages provide supporting background, literature notes, and claim-level evidence used to keep manuscript statements traceable.