E-MTAB-5061

E-MTAB-5061 is an ArrayExpress dataset containing single-cell RNA-seq data from human pancreatic tissue and islets.

Details

  • Tissue: Pancreatic tissue and islets
  • Participants: 6 healthy controls, 4 T2D donors
  • Platform: scRNA-seq (10x Genomics)
  • Use in Huang et al. 2022: Cell clustering identified 13 clusters annotated to 6 cell types; SERPINF1 localization in fibroblasts; NR2F2 TF analysis via SCENIC.
  • Original study: Segerstolpe et al. 2016 (Cell Metabolism)

Cell Types Identified

  1. Epithelial cells
  2. Fibroblasts
  3. Neurons
  4. Endothelial cells
  5. Macrophages
  6. Hepatocytes